The Department of Obstetrics and Gynaecology has two broad areas of research activity. The first covers the use of large population databases to identify key predictive features associated with human pregnancy, such as intrauterine growth restriction, preterm labour and perinatal death.The second major area focuses on the cellular and molecular aspects of the growth of the placenta and its interaction with the endometrium. This includes a detailed investigation of the immune dialogue occurring between the fetal and maternal compartments. Genetic and epigenetic modulation of placental function is also a key area within this field. Modern genomic methods are utilised in both human and genetically manipulated animal models.
Cambridge, United Kingdom
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