MSc in Diagnostics and Precision Medicine

at Dublin City University

The MSc in Diagnostics and Precision Medicine is a blended-learning programme that details how diagnostics and therapeutics are revolutionising healthcare and medicine by providing the right person with the right therapy at the right time.

Recent advances in the understanding of normal and diseased states has led to revolutionary new treatments for conditions such as cancer, inflammatory diseases and inherited diseases. Furthermore, advances in science and technology have resulted in the development of new biomedical assays to (a) diagnose diseases and conditions more accurately (b) classify disease more precisely (c) approach treatment more individually and (d) identify who is at risk of developing a disease or condition.

Such advances in diagnostics and therapeutics have ushered in an exciting new era known as Precision Medicine, which refers to prevention and treatment strategies that takes patient variability into account (people’s genes, environment and lifestyles) by providing the right patient with the right medicine at the right time. As an example, the treatment of several cancers have shifted away from the “One-Size-Fits-All” approach of treatment (e.g. chemotherapy) to a more focused and tailored strategy where targeted therapies are matched according to the molecular profile of a patient’s tumour. In this situation, variations in the sequence, structure or expression of that person’s DNA, RNA or protein (i.e. biomarkers) are analysed using clinically-validated diagnostic assays (commonly referred to as Companion Diagnostics) and used to stratify patients so that those who are likely to benefit from these therapies are identified and treated, while who are unlikely to benefit (and may experience unnecessary side effects) can receive alternative treatments.  Similarly, molecular diagnostic assays are increasing used to predict the outcome of a patient’s disease (prognosis), and therefore medical treatments can be tailored accordingly.